Development of
Carbohydrate-based Therapeutic and Anti-infective Compounds
My
research group has developed expedient methodologies for the preparation of a
library of structurally diverse unusual sugars. These unusual sugars can be
incorporated stereoselectively onto selective molecules, generating a library of
glycosylated compounds with immense biological interest: a strategy, which we
called, glycodiversification. Using glycodiversification strategy, my group can
quickly evaluate the properties of sugar-containing molecules, leading to
various applications in areas including chemistry, biology, medicinal chemistry,
and pharmacy. Several distinct but cooperative projects are being conducted:
Project
1: Development of Aminoglycoside Antibiotics
Project
3: Development of Novel Antitubercular Agents
Project
4: Development of Technologies for
Complex Carbohydrate Synthesis
Project
5: Development of Carbohydrate Conjugates
Project 6: Development of Novel Antifungal Agents
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