"Ongoing projects are examining the chemistry of phosphoryl
and sulfuryl esters. These compounds have great importance in biological
systems, where their hydrolysis and their formation are catalyzed
with remarkable efficiency by enzymes at rates millions of times
(or more) faster than the analogous uncatalyzed reactions. Our research
seeks to understand this chemistry, and how enzymes achieve these
remarkable rate accelerations."
:: Contact
Professor Alvan Hengge
Department of Chemistry and Biochemistry
Utah State University
Logan, UT 84322-0300 USA
Office phone: (435) 797-3442, FAX: (435) 797-3390
Lab phone: (435) 797-0023
E-mail: hengge@cc.usu.edu
:: Hotspot
Diesterase Activity and Substrate
Binding in Purple Acid Phosphatases
Robynn S. Cox, Gerhard Schenk, Natasa Mitic, Lawrence R. Gahan,
and Alvan C. Hengge J. Am. Chem. Soc.; 2007; 129(31) pp
9550 - 9551; (Communication) DOI: 10.1021/ja072647q
