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Tom Chang

Profile Picture

Organic Chemistry

Professor

Contact Information

DialPhone: (435) 797-3545
SendEmail: tom.chang@usu.edu


Educational Background

PhD, Washington University, 1997
MA, Washington University, 1994
BS, Tunghai University, 1988

Biography

B.S. 1988, Tunghai University, Taiwan Ph.D. 1997, Washington University, St. Louis, Missouri Post-Doctoral, 1997-1999 University of Minnesota


Teaching Interests

Chem2300 Principles of Organic Chemistry Chem2320 Organic Chemistry II Chem1120 General Chemistry II Chem5530 Advanced Synthesis Chem 7300 Reactions and Synthesis in Modern Organic Chemistry

Research Interests

Dr. Chang has developed his research program that encompasses chemistry, biology, and microbiology. His research team has been engaging in multiple projects that expand from antibacterial, antifungal, antiviral, and anticancer areas with leads identified in every category. His research focuses not only on product development but also on basic science. New projects even include alternative energy development and antiviral agent through green chemistry.

Awards

College of Science, Undergraduate Research Mentor of the Year, 2015

Researcher of the Year, 2010

USU College of Science

Gardner Junior Faculty Travel Award, 2006

Utah State University

Accounts of Chemical Research Graduate Prize, 1994

Natural Science Scholarship , 1988

Tunghai University

Natural Science Scholarship , 1987

Tunghai University

Publications - Abstracts

  • Anderson, S.N, Nziko, Vincent de Paul Nzuwah, , Chang, C.T, Hengge, A.C, (2014). Enhancing safety in academic research laboratories: Creating a studentbased safety committee. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY *

Publications - Books & Book Chapters

    Book Chapters

  • Wang, J., Chang, C.T, (2007). Design, Chemical Synthesis, and Antibacterial Activity of Kanamycin and Neomycin Class Aminoglycoside Antibiotics: Aminoglycoside Antibiotics . John Wiley & Sons, Inc.
  • Wang, J., Chang, C.T, (2007). Glycodiversification for the Synthesis of Kanamycin and Neomycin Class Aminoglycoside Antibiotics: Frontiers in Carbohydrate Chemistry. ACS Symposium Series
  • Wang, J., Chang, C.T, (2005). Systematic Synthesis of Aminosugars and Their Stereoselective Glycosylation: Carbohydrate Drug Design. ACS Symposium Series

* Has not been peer reviewed

Publications - Fact Sheets

    * Has not been peer reviewed

    Publications - Curriculum

      * Has not been peer reviewed

      Publications - Journal Articles

        Academic Journal

      • Shrestha, J., Colman, B., Kawasaki, Y., Nziko, V., Subedi, Y., Takemoto, J.Y, Chang, C.T, (2017). Synthesis and Bioactivity Investigation of Quinone-based Dimeric Cationic Triazolium Amphiphiles Selective against Resistant Fungal and Bacterial Pathogens. Eur. J. Med. Chem., 126, 596.
      • Shrestha, S.K, Grilley, M.M, Anderson, T., Dhiman, C., Oblad, J., Chang, C.T, Sorensen, K.N, Takemoto, J.Y, (2015). In vitro antifungal synergy between amphiphilic aminoglycoside K20 and azoles against Candida species and Cryptococcus neoformans. Med Mycol
      • Zhang, Q., Peng, X., Grilley, M.M, Takemoto, J.Y, Chang, C.T, (2015). Using Fluorogenic Probes for the Investigation of Selective Biomass Degradation by Fungi. Green Chem, 17, 1918-1925.
      • Shrestha, S.K, Chang, C.T, Meissner, N., Oblad, J., Shrestha, J.P, Sorensen, K.N, Grilley, M.M, Takemoto, J.Y, (2014). Antifungal amphiphilic aminoglycoside K20: bioactivities and mechanism of action. Frontiers in Microbiology, 5:271, 1-12. doi: doi: 10.3389/fmicb.2014.00671
      • Chang, C.T, Takemoto, J.Y, (2014). Antifungal amphiphilic aminoglycosides. Med. Chem. Comm., 5, 1048-1057.
      • Lee, S.T, Green, B.T, Welch, K.D, Jordan, G.T, Zhang, Q., Panter, K.E, Hughe, D., Chang, C.T, Pfister, J.A, Gardner, D.R, (2013). Stereoselective Potencies and Relative Toxicities of γ-Coniceine, and N-Methylconiine Enantiomers. Chemical Research in Toxicology, 26, 616-621.
      • Shrestha, S., Grilley, M.M, Fosso, M.Y, Chang, C.T, Takemoto, J.Y, (2013). Membrane lipid-modulated mechanism of action and non-cytotoxicity of novel fungicide aminoglycolipid FG08. PLoS One, doi: 8:e73843
      • Shrestha, S., Grilley, M.M, Fosso, M.Y, Chang, C.T, Takemoto, J.Y, (2013). Membrane Lipid-Modulated Mechanism of Action and Non-Cytotoxicity of Novel Fungicide Aminoglycoside FG08. PloS one, 8:9, e73843.
      • Mattis, V.B, Chang, C.T, Lorson, C.L, (2012). Analysis of a read-through promoting compound in a severe mouse model of Spinal Muscular Atrophy. Neurosci. Lett. , 525, 72-75.
      • Lee, S.T, Panter, K.E, Gardner, D.R, Green, B.T, Welch, K.D, Zhang, J., Chang, C.T, (2012). Development of a monoclonal antibody-based ELISA for the hedgehog inhibitors cyclopamine and cyclopamine-KAAD. J. Pharmaceut. Biomed. Anal., 66, 282-286.
      • Zhang, J., Redman, N., Litke, P., Zeng, J., Zhan, J., Chan, K.Y, Chang, C.T, (2011). Synthesis and Antibacterial Activity Study of a Novel Class of Cationic Anthraquinone Analogs. Bioorganic Medicinial Chemistry, 19, 498-503.
      • Tanifum, C.T, Zhang, J., Chang, C.T, (2010). Combination of Solid Phase and Solution Phase Synthesis of Oligosaccharides Using Sonication. Tetrahedron Letters, 51, 4323-4327.
      • Zhang, J., Litke, A., Keller, K., Rai, R., Chang, C.T, (2010). Synthesis of Novel Aminoglycosides via Allylic Azide Rearrangement for Investigating the Significance of 2'-Amino Group. Bioorganic Medicinal Chemistry, 18, 1396-1405.
      • Mattis, V.B, Ebert, A.D, Fosso, M.Y, Chang, C.T, Lorson, C.L, (2009). Delivery of a read-through inducing compound, TC007, lessens the severity of a SMA animal model. Human Molecular Genetics, 18, 3906-3913.
      • Zhang, J., Chang, C.T, (2009). Divergent Synthesis of Three Classes of Aryl N-Glycosides by Solvent Control. Journal of Organic Chemistry, 74, 685-695.
      • Zhang, J., Chang, C.T, (2009). One-pot Synthesis of 1- and 2-Substituted Naphtho[2,3-d][1,2,3]triazole-4,9-diones. Journal of Organic Chemistry, 74, 4414-4417.
      • Chang, C.T, (2009). Predictable Enzymatic Glycosylation. Chemical Biology, 16, 579-580.
      • Tanifum, C.T, Chang, C.T, (2009). Sonication-Assisted Oligomannosides Syntheses. Journal of Organic Chemistry, 74, 4414-4417.
      • Zhang, J., Keller, K., Takemoto, J.Y, Bensaci, M., Litke, A., Crzyryca, P.G, Chang, C.T, (2009). Synthesis and Combinational Antibacterial Study of 5"-Modified Neomycin. The Journal of Antibiotics, 62, 539-544.
      • Lee, S.T, Gardner, D.R, Chang, C.T, Panter, K.E, Molyneux, R.J, (2008). Separation of Measurement of Plant Alkaloid Enantiomers by RF-HPLC Analysis of Their Fmoc-Alanine Analogs. Phytochemical Analysis, 19, 395-402.
      • Zhang, J., Chiang, F., Wu, L., Czyryca, G.P, Li, D., Chang, C.T, (2008). Surprising Alteration of Antibacterial Activity of 5"-Modified Neomycin against Resistant Bacteria. Journal of Medicinal Chemistry, 51, 7563-7573.
      • Zhang, J., Garrossian, M., Gardner, D., Garrossian, A., Chang, Y., Kim, Y.K, Chang, C.T, (2008). Synthesis and Anticancer Activity Studies of Cyclopamine Derivatives. Bioorganic & Medicinal Chemistry Letters, 18, 1359-1363.
      • Zhang, J., Garrossian, M., Gardner, D., Garrossian, A., Chang, Y., Kim, Y.K, Chang, C.T, (2008). Synthesis and Anticancer Activity Studies of Cyclopamine Derivatives. Bioorganic & Medicinal Chemistry Letters, 18, 1359-1363.
      • Li, J., Chiang, F., Chen, H., Chang, C.T, (2007). Investigation of the Regioselectivity for Staudinger Reaction and Its Application for the Synthesis of Aminoglycosides with N-1 Modification. J. Org. Chem., 72, 4055-4066.
      • Zhang, J., Chen, H., Chiang, F., Takemoto, J.Y, Bensaci, M., Chang, C.T, (2007). Sonication-Assisted Library Synthesis of Oxazolidinone-Carbohydrate Conjugates. J. Comb. Chem., 9, 17-19.
      • Li, J., Wang, J., Chiang, F., Chen, H.N, Chang, C.T, (2007). Synthesis of Pyranmycin Derivatives with N-1 and O-6 Modifications. Bioorg. Med. Chem. , 15, 7711-7719.
      • Deng, S., Chang, C.T, (2006). Acyl Migration for the Construction of Disaccharides. Synlett, 756-760.
      • Rai, R., Chen, H., Czyryca, P.G, Li, J., Chang, C.T, (2006). Design and Synthesis of Pyrankacin: A Pyranmycin Class Broad Spectrum Aminoglycoside Antibiotic. Org. Lett., 8, 887-889.
      • Mattis, V., Wang, J., Rai, R., Chang, C.T, Lorson, C.L, (2006). Novel Aminoglycosides Increase SMN Levels in Spinal Muscular Atrophy fibroblasts. Human Genetics , 120, 589-601.
      • Li, J., Chang, C.T, (2006). Recent Development in the Synthesis of Novel Aminoglycoside Antibiotics. Anti-Infective Agents in Medicinal Chemistry , 5, 255-271.
      • Lee, S.T, Wildeboer, K., Panter, K.E, Kem, W.R, Gardner, D.R, Molyneux, R.J, Chang, C.T, Soti, F., Pfister, J.A, (2006). Relative toxicities and neuromuscular nicotinic receptor agonistic potencies of anabasine enantiomers and anabaseine. Neurotoxicology and Teratology, 28, 220-228.
      • Deng, S., Gandafharmath, U., Chang, C.T, (2006). Sonochemistry: A Powerful Way of Enhancing the Efficiency of Carbohydrate Synthesis. J. Org. Chem. , 71, 5179-5185.
      • Lee, S.T, Molyneux, R.J, Panter, K.E, Chang, C.T, Gardner, D.R, Pfister, J.A, Garrossian, M., (2005). Ammodendrine and N-Methylammodendrine Enantiomers: Isolation, Optical Rotation, and Toxicity. J. Nat. Prod., 68, 681-685.
      • Wang, J., Li, J., Chen, H., Chang, H., Tanifum, C.T, Liu, H., Czyryca, P.G, Chang, C.T, (2005). Glycodiversification for Optimization of the Kanamycin Class Aminoglycosides. J. Med. Chem. , 48, 6271-6285.
      • Wang, J., Li, J., Chen, H., Chang, H., Tanifum, C.T, Liu, H., Czyryca, P.G, Chang, C.T, (2005). Glycodiversification for Optimization of the Kanamycin Class Aminoglycosides. J. Med. Chem. , 48, 6271-6285.
      • Rai, R., Chang, H., Chen, H., Chang, C.T, (2005). Novel Method for the Synthesis of 3’,4’-Dideoxygenated Pyranmycin and Kanamycin Compounds, and Studies of Their Antibacterial Activity against Aminoglycoside Resistant Bacteria. J. Carbohydr. Chem. , 24, 131-143.
      • Rai, R., Chang, H., Chen, H., Chang, C.T, (2005). Novel Method for the Synthesis of 3’,4’-Dideoxygenated Pyranmycin and Kanamycin Compounds, and Studies of Their Antibacterial Activity against Aminoglycoside Resistant Bacteria. J. Carbohydr. Chem. , 24, 131-143.
      • Rai, R., McAlexander, I., Chang, C.T, (2005). Synthetic Glycodiversification: from Aminosugars to Aminoglycoside Antibiotics. Organic Preparations and Procedures International, 37, 337-375.
      • Li, J., Chen, H., Chang, H., Wang, J., Chang, C.T, (2005). Tuning the Regioselectivity of Staudinger Reaction for the Facile Synthesis of Kanamycin and Neomycin Class Antibiotics with N-1 Modification. Org. Lett., 7, 3061-3064.
      • Li, J., Chen, H., Chang, H., Wang, J., Chang, C.T, (2005). Tuning the Regioselectivity of Staudinger Reaction for the Facile Synthesis of Kanamycin and Neomycin Class Antibiotics with N-1 Modification. Org. Lett., 7, 3061-3064.
      • Li, J., Wang, J., Czyryca, P.G, Chang, H., Orsak, T.W, Evanston, R., Chang, C.T, (2004). Application of Glycodiversification: Expedient Synthesis and Antibacterial Evaluation of a Library of Kanamycin B Analogs. Org. Lett., 6, 1381-1384.
      • Li, J., Wang, J., Czyryca, P.G, Chang, H., Orsak, T.W, Evanston, R., Chang, C.T, (2004). Application of Glycodiversification: Expedient Synthesis and Antibacterial Evaluation of a Library of Kanamycin B Analogs. Org. Lett., 6, 1381-1384.
      • Elchert, B., Li, J., Wang, J., Hui, Y., Rai, R., Ptak, R., Ward, P., Takemoto, J.Y, Bensaci, M., Chang, C.T, (2004). Application of the Synthetic Aminosugars for Glycodiversification: Synthesis and Antimicrobial Studies of Pyranmycin. J. Org. Chem. , 69, 1513-1523.
      • Wang, J., Li, J., Czyryca, P.G, Chang, H., Kao, J., Chang, C.T, (2004). Synthesis of an Unusual Branched-chain Sugar, 5-C-methyl-L-idopyranose for SAR Studies of Pyranmycins: Implications for the Future Design of Aminoglycoside Antibiotics. Bioorg. Med. Chem. Lett. , 14, 4389-4393.
      • Wang, J., Li, J., Czyryca, P.G, Chang, H., Kao, J., Chang, C.T, (2004). Synthesis of an Unusual Branched-chain Sugar, 5-C-methyl-L-idopyranose for SAR Studies of Pyranmycins: Implications for the Future Design of Aminoglycoside Antibiotics. Bioorg. Med. Chem. Lett. , 14, 4389-4393.
      • Wang, J., Elchert, B., Hui, Y., Takemoto, J.Y, Bensaci, M., Wennergren, J., Chang, H., Rai, R., Chang, C.T, (2004). Synthesis of Trehalose-based Compounds and Study of Their Antibacterial Activity against Mycobacterium smegmatis. Bioorg. Med. Chem. , 12, 6397-6413.
      • Wang, J., Elchert, B., Hui, Y., Takemoto, J.Y, Bensaci, M., Wennergren, J., Chang, H., Rai, R., Chang, C.T, (2004). Synthesis of Trehalose-based Compounds and Study of Their Antibacterial Activity against Mycobacterium smegmatis. Bioorg. Med. Chem. , 12, 6397-6413.
      • Li, J., Wang, J., Hui, Y., Chang, C.T, (2003). Exploring the Optimal Site for Modification of Pyranmycin with the Extended Arm Approach. Org. Lett. , 5, 431-434.
      • Leriche, C., He, X., Chang, C.T, Liu, H., (2003). Reversal of the Apparent Regiospecificity of NAD(P)H-Dependent Hydride Transfer: The Properties of the Difluoromethylene Group, A Carbonyl Mimic. J. Am. Chem. Soc., 125, 6348-6349.
      • Hui, y., Chang, C.T, (2002). A Convenient Divergent Synthesis of A library of Trehalosamine Analogs. Org. Lett. , 4, 2245-2248.
      • Chen, H., Yamase, H., Zhao, L., Chang, C.T, Murakami, K., Liu, H., (2002). N, N-Dimetyltransferases, TylM1 and DesVI, Involved in the Biosynthesis of Mycaminose and Desosamine: Expression, Purification and Characterization. Biochemistry, 29, 9165-9183.
      • Chang, C.T, Hui, Y., Elchert, B., Wang, J., Li, J., Rai, R., (2002). Pyranmycins, a novel class of aminoglycosides with improved acid stability: the SAR of D-pyranoses on ring III of pyranmycin. Org. Lett. , 4, 4603-4606.
      • Hui, Y., Ptake, P., Paulman, R., Pallansch, M., Chang, C.T, (2002). Synthesis of Novel Guanidine Incorporated Aminoglycosides, Guanidinopyranmycins. Tetrahedron Lett. , 43, 9255-9257.
      • Chang, C.T, Liu, H., (2002). Synthesis of TDP-3-amino-3,4,6-trideoxy-a-D-xylo-hexopyranose-The immediate precursor of TDP-a-D-desosamine. Bioorg. Med. Chem. Lett., 12, 1439-1496.
      • Wang, J., Li, J., Tuttle, D., Takemoto, J., Chang, C.T, (2002). The synthesis of L-aminosugar and the studies of L-pyranoses on the ring III of pyranmycins. Org. Lett. , 4, 3997-4000.
      • Chang, C.T, Clark, T., Ngaara, M., (2001). Novel and Convenient Method for the Synthesis of 2,6-Dideoxypyranoses, 3,6-Dideoxypyranoses, and Azido (amino) Analogs of 3,6-Dideoxypyranoses. Tetrahedron Lett. , 42, 6797-6801.
      • Chang, C.T, Hui, Y., Elchert, B., (2001). Studies of the Stereoselective Reduction of Ketosugar (Hexosulose). Tetrahedron Lett, 42, 7019-7023.
      • Professional Journal

      • Sun, L., Wang, S., Zhang, S., Shao, L., Zhang, Q., Skidmore, C., Chang, C.T, Chang, C.T, Yu, D., Zhan, J., (2016). Characterization of three tailoring enzymes in dutomycin biosynthesis and generation of a potent antibacterial analogue. ACS Chemical Biology , 11, 1992.
      • Sun, L., Wang, S., Zhang, S., Shao, L., Zhang, Q., Skidmore, C., Chang, C.T, Chang, C.T, Yu, D., Zhan, J., (2016). Characterization of three tailoring enzymes in dutomycin biosynthesis and generation of a potent antibacterial analogue. ACS Chemical Biology , 11, 1992.
      • Zhang, Q., Alfindee, M., Shrestha, J., Nziko, V., Kawasaki, Y., Peng, X., Takemoto, J., Chang, C.T, (2016). Divergent Synthesis of Three Classes of Antifungal Amphiphilic Kanamycin Derivatives. JOC, 81, 10651.
      • Zhang, Q., Chang, C.T, (2015). Divergent and Facile Lewis Acid-Mediated Synthesis of N-Alkyl 2-aminomethylene-1,3-indanediones and 2-Alkylamino-1,4-Naphthoquinones. Tetrahedron Lett, 56, 893.
      • Shrestha, J., Subedi, Y., Chen, L., Chang, C.T, (2015). Mode of Action Study of Cationic Anthraquinone Analog: A New Class of Highly Potent Anti-cancer Agent. MedChemComm, 2012.
      • Fosso, M., AlFindee, M., Zhang, Q., Nziko, V., Kawasaki, Y., Shrestha, S., Bearss, J., Gregory, R., Takemoto, J., Chang, C.T, (2015). Structure–Activity Relationships for Antibacterial to Antifungal Conversion of Kanamycin to Amphiphilic Analogues. J Org Chem, 80, 4398.
      • Nziko, , Fosso, M., Chang, C.T, (2014). Quantitative structure activity relationship analysis of antibacterial cationic anthraquinone analogs using Hansch and Fujita models. Med. Chem. Res, 23, 5058-5062.
      • Shretha, J., Fosso, M.Y, Bearss, J., Chang, C.T, (2014). Synthesis and anticancer structure activity relationship investigation of cationic anthraquinone analogs. Eur. J. Med. Chem. , 77, 96-102.
      • Zhang, Q., Shretha, J., Chang, C.T, (2014). Synthesis of bioactive 1-alkyl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-diones and N-aryl-2-aminomethylene-1,3-indanediones using water as the solvent. Tetrahedron Lett, 55, 1839-1842.
      • Udumula, U., Ham, Y., Fosso, M., Chen, K., Rai, R., Zhang , J., Li, J., Chang, C.T, (2013). Investigation of Antibacterial Mode of Action for Traditional and Amphiphilic Aminoglycosides.. Bioorg Med Chem Lett, 23, 1671-1675.
      • Ito, T., Chen, D., Chang, C.T, Kenmochi, T., Saito, T., Suzuki, S., Takemoto, J.Y, (2013). Meso-biliverdin IX and Biliverdin IX Provide Cytoprotection of Rat Pancreatic Islets. Frontiers in Pharmacology 4, 1-8.
      • Shretha, J., Chang, C.T, (2013). Safe and Easy Route for the Synthesis of 1,3-Dimethyl-1,2,3-triazolium Salt and Investigation of Its Anticancer Activities. Bioorg Med Chem Lett, 23, 5909-5911.
      • Fosso, M., Nziko, V., Chang, C.T, (2012). Chemical Synthesis of N-Aryl Glycosides. J. Carbohydr. Chem., 31, 603.
      • Fosso, M., Chen, K., Gregory, R., Chang, C.T, (2012). Library Synthesis and Antibacterial Investigation of Cationic Anthraquinone Analogs. ACS, 14, 231.
      • Chan, K., Zhang, J., Chang, C.T, (2011). Mode of Action Investigation for the Antibacterial Cationic Anthraquinone Analogs.. Bioorg. Med. Chem. Lett. , 21, 6353.

      * Has not been peer reviewed

      Publications - Literary Journal

        * Has not been peer reviewed

        Publications - MultiMedia

          * Has not been peer reviewed

          Publications - Technical Reports

            * Has not been peer reviewed

            Publications - Translations & Transcripts

              Publications - Other

                Other

              • Takemoto, J.Y, Chen, D., Chang, C.T, Jonathan, W.L, (2015). Therapeutic mesobiliverdin IXalpha compositions and associated methods, Patent assigned, US9119842 B2. United States Patent Office
              • Takemoto, J.Y, Chen, D., Chang, C.T, Jonathan, W.L, (2014). Therapeutic compositions and associated methods. World Intellectual Property Organization

              * Has not been peer reviewed

              Scheduled Teaching

              CHEM 2320 - Organic Chemistry II, Spring 2017

              CHEM 7300 - Reactions and Synthesis in Modern Organic Chemistry, Spring 2017

              CHEM 2300 - Principles of Organic Chemistry, Fall 2016

              CHEM 2320 - Organic Chemistry II, Summer 2016

              CHEM 5530 - Advanced Synthesis Laboratory, Spring 2016

              CHEM 4800 - Research Problems, Spring 2016

              CHEM 2300 - Principles of Organic Chemistry, Fall 2015

              CHEM 2320 - Organic Chemistry II, Summer 2015

              CHEM 5530 - Advanced Synthesis Laboratory, Spring 2015

              CHEM 2300 - Principles of Organic Chemistry, Fall 2014

              CHEM 2320 - Organic Chemistry II, Summer 2014

              CHEM 5530 - Advanced Synthesis Laboratory, Spring 2014

              CHEM 7300 - Reactions and Synthesis in Modern Organic Chemistry, Spring 2014

              CHEM 2300 - Principles of Organic Chemistry, Fall 2013

              CHEM 2320 - Organic Chemistry II, Summer 2013

              CHEM 7300 - Reactions and Synthesis in Modern Organic Chemistry, Fall 2012

              CHEM 4800 - Research Problems, Fall 2012

              CHEM 7800 - Seminar, Fall 2012

              CHEM 5530 - ADV SYNTHESIS LAB, Spring 2012

              CHEM 1120 - General Chemistry II, Spring 2012

              CHEM 7800 - Seminar, Spring 2012

              CHEM 2300 - Principles of Organic Chemistry, Fall 2011

              CHEM 5530 - ADV SYNTHESIS LAB, Spring 2011

              CHEM 7970 - DISSERTATION RSRCH, Spring 2011

              CHEM 7300 - REACT/SYN ORG CHEM, Spring 2011

              CHEM 7970 - PhD Dissertation Research, Fall 2010

              CHEM 2300 - Principles of Organic Chemistry, Fall 2010


              Graduate Students Mentored